A research programme for selected patients, with advanced retinal diagnostics and close monitoring.
At The Retina Clinic London, clinical trials form an important part of our research programme in retinal disease. We work with research partners on ethically approved studies assessing investigational treatments and new ways of monitoring retinal conditions. Participation is always voluntary, places are limited, and suitability is confirmed through a structured screening process.
Who this page is for
For optometrists and referrers: a clear overview of trial areas currently assessing suitability, plus how to refer.
For patients: what a clinical trial is, what participation may involve, and how to enquire.
Current recruiting clinical trials
Trial availability can change quickly. The pages below outline the study area, broad eligibility considerations, and how to enquire, but do not guarantee immediate screening or enrolment.
- Geographic Atrophy (GA) secondary to Dry Age-related Macular Degeneration (AMD) trials – read more
- Wet Age-related Macular Degeneration (AMD) trials – read more
- Diabetic eye disease trials – read more
- Retinal Vein Occlusion trials – read more
- Vitreous floaters and opacities (VFO) trials
Inherited retinal dystrophy trials
For optometrists: when a trial referral may help
A trial may be relevant when a patient has a confirmed diagnosis and:
- is interested in additional research options alongside, or after, standard care, or
- has a condition where approved treatment options are limited, evolving, or not suitable for every patient.
We are selective and follow study criteria closely. To help avoid unnecessary appointments, we may be able to pre-screen using imaging obtained in your practice. In some cases, we may also invite the patient for study-specific imaging at no charge before formal screening is considered.
How to refer
Please provide:
- diagnosis and key ocular history
- current VA (visual acuity)
- OCT, fundus photos, and any relevant previous imaging, if available
- current and recent ocular treatments, if any
We will respond with whether screening is likely to be appropriate, and the next steps.
For patients: what a clinical trial is (and is not)
A clinical trial is a research study that evaluates an investigational treatment or approach to managing a condition. Some research studies assess investigational treatments, while others are observational and help us understand how retinal diseases progress or how they can be monitored over time.
Trials can offer access to something not yet widely available, but they do not guarantee benefit. If you decide to proceed, we will explain the purpose of the study, what participation may involve, the visit schedule, and the potential risks and possible benefits clearly before any formal screening and as part of the informed consent process.
a. Eligibility: a careful, selective process
Not everyone who enquires can take part. Each study has specific criteria and limited capacity.
b. Typical steps:
- Enquiry or referral
- Pre-screen review (to check likely suitability)
- Screening appointment (diagnostics and eligibility confirmation)
- Enrolment (only if eligible and a place is available)
- Costs and practical support
In many studies, study-related assessments, imaging, and investigational treatment are covered by the study sponsor. Some studies may also offer travel reimbursement within defined limits. We will explain exactly what is covered for the specific study before any screening visit.
Why trials at The Retina Clinic London
Our clinical trials programme is supported by advanced retinal imaging, specialist diagnostics, and close follow-up by an experienced multidisciplinary team. For selected studies, this can help us assess suitability carefully and monitor participants in detail throughout the research pathway.
Find out more
Optometrists: please contact our Clinical Trials team with a summary and imaging.
Patients: contact us directly and we can advise whether a trial may be worth exploring.